RNF20

Across TCGA cell cohorts, RNF20 mutation is significantly associated with the RNA expression of many other genes, with 1,060 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RNF20-associated genes across cancer lineages are BTNL3, ISX, and TDGF1. Each is linked with RNF20 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF20-to-partner and partner-to-RNF20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BTNL3 grouped by RNF20-low versus RNF20-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF20→partner) and Y-score (partner→RNF20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	BTNL3 →	+0.222	+3.451	.009	.008	3	1
PANCREAS	ISX →	+0.738	+4.146	<.001	.002	3	1
PANCREAS	TDGF1 →	+0.255	+3.209	.002	.005	3	1
UPPER_AERODIGESTIVE_TRACT	MTRNR2L6 →	+0.173	+5.357	<.001	.003	3	1
UPPER_AERODIGESTIVE_TRACT	TFAP2D →	+0.116	+4.736	<.001	.009	3	1
LARGE_INTESTINE	SRRD →	+0.630	+3.169	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,060 associations by consensus.

BTNL3 by RNF20 expression — PANCREAS

Explore this box plot interactively →