RNF2

Across TCGA cell cohorts, RNF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,396 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RNF2-associated GO terms across cancer lineages are Heterochromatin formation, Epigenetic regulation of gene expression, and Nuclear pore organization. Each is linked with RNF2 in more than 12 cancer types. Because this analysis shows association rather than direction, both RNF2-to-partner and partner-to-RNF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin formation grouped by RNF2-low versus RNF2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF2→partner) and Y-score (partner→RNF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Heterochromatin formation →	+0.076	+0.911	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Epigenetic regulation of gene expression →	+0.074	+0.998	<.001	<.001	3	13
SOFT_TISSUE	Nuclear pore organization →	+0.165	+0.696	<.001	<.001	3	13
SOFT_TISSUE	RNA export from nucleus →	+0.117	+0.775	<.001	<.001	3	13
BONE	mRNA export from nucleus →	+0.123	+1.106	.001	.001	3	13
SOFT_TISSUE	Mitotic nuclear division →	+0.105	+0.857	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,396 associations by consensus.

Heterochromatin formation by RNF2 expression — OVARY

Explore this box plot interactively →