Across TCGA pan-cancer cohorts, RNF19BPY RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of RNF19BPY’s most consistent transcriptional readouts.
The strongest signal is observed in esophageal carcinoma (ESCA), where RNF19BPY RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNF19BPY is over-expressed in tumor.
ESCA are the cancer types where RNF19BPY tumor–normal differential expression is most reproducible.