RNF187

Across TCGA pan-cancer cohorts, RNF187 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated RNF187 data layer compared with 27 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher RNF187 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNF187 expression acts as an unfavorable survival marker.

LSCC, HNSC, and CCRCC are the cancer types where RNF187 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	All	0.488	0.846	.004	18	view →
HNSC	DFS	Quartile	IV	0.490	0.783	.014	11	view →
CCRCC	OS	Median	All	0.815	0.955	.014	5	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

RNF187–LSCC (DFS)

Open the LSCC breakdown →