RNF187

Across TCGA patient cohorts, RNF187 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF187-associated genes across cancer lineages are CHURC1-FNTB, MIR425, and RNA5SP124. Each is linked with RNF187 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF187-to-partner and partner-to-RNF187 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHURC1-FNTB grouped by RNF187-low versus RNF187-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF187→partner) and Y-score (partner→RNF187) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CHURC1-FNTB →	+0.068	+3.736	.005	.004	3	1
UCEC	MIR425 →	+0.718	+3.329	<.001	.004	3	1
UCEC	RNA5SP124 →	+0.576	+2.996	<.001	.009	3	1
UCEC	RNU6-1082P →	+0.507	+4.136	<.001	.001	3	1
UCEC	RNU6-4P →	+0.682	+3.649	.004	.005	3	1
UCEC	RNU6-39P →	+0.439	+3.492	.008	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

CHURC1-FNTB by RNF187 expression — UCEC

Explore this box plot interactively →