RNF187

Across TCGA cell cohorts, RNF187 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,322 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNF187-associated GO terms across cancer lineages are Positive regulation of protein sumoylation, Regulation of protein sumoylation, and Regulation of phospholipid translocation. Each is linked with RNF187 in more than 10 cancer types. Because this analysis shows association rather than direction, both RNF187-to-partner and partner-to-RNF187 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein sumoylation grouped by RNF187-low versus RNF187-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF187→partner) and Y-score (partner→RNF187) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Positive regulation of protein sumoylation →	+0.096	+0.731	.004	.007	3	11
SKIN	Regulation of protein sumoylation →	+0.092	+0.698	.003	<.001	3	11
OESOPHAGUS	Regulation of phospholipid translocation →	-0.246	-1.258	<.001	.007	3	10
OESOPHAGUS	Positive regulation of phospholipid translocation →	-0.246	-1.258	<.001	.007	3	10
STOMACH	Calcium-independent cell-matrix adhesion →	+0.155	+0.649	<.001	<.001	3	10
BONE	Transport along microtubule →	+0.065	+1.263	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,322 associations by consensus.

Positive regulation of protein sumoylation by RNF187 expression — LARGE_INTESTINE

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