RNF186

Across TCGA patient cohorts, RNF186 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,197 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible RNF186-associated proteins across cancer lineages are ARHGEF2, CEP170_S881, and CLMN. Each is linked with RNF186 in more than 2 cancer types. Because this analysis shows association rather than direction, both RNF186-to-partner and partner-to-RNF186 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF186 versus ARHGEF2 in COAD, with a Pearson correlation of -0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF186→partner) and Y-score (partner→RNF186) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ARHGEF2 →	-0.275	-1.310	<.001	<.001	3	3
COAD	CEP170_S881 →	-0.364	-0.970	<.001	<.001	3	3
PDAC	CLMN →	+0.326	+0.835	<.001	<.001	3	3
COAD	CLMN_S301 →	+0.487	+0.832	<.001	<.001	3	3
CCRCC	DPYD →	-0.376	-1.541	.001	<.001	3	3
COAD	ENTPD5 →	+0.626	+1.196	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,197 associations by consensus.

RNF186 vs ARHGEF2 — COAD

Explore this scatter interactively →