RNF185

Across TCGA patient cohorts, RNF185 protein abundance is significantly associated with the RNA expression of many other genes, with 8,109 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF185-associated genes across cancer lineages are RTCB, UQCR10, and ARRB1. Each is linked with RNF185 in more than 4 cancer types. Because this analysis shows association rather than direction, both RNF185-to-partner and partner-to-RNF185 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF185 versus RTCB in OV, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF185→partner) and Y-score (partner→RNF185) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RTCB →	+0.666	+0.637	<.001	<.001	3	5
OV	UQCR10 →	+0.530	+0.509	.004	.005	3	5
HNSC	ARRB1 →	-0.537	-0.363	.001	<.001	3	5
LSCC	UBE2L3 →	+0.392	+0.316	<.001	<.001	3	5
LSCC	PES1 →	+0.455	+0.260	<.001	<.001	3	4
OV	DRG1 →	+0.427	+0.470	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,109 associations by consensus.

RNF185 vs RTCB — OV

Explore this scatter interactively →