RNF180

Across TCGA cell cohorts, RNF180 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,130 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible RNF180-associated GO terms across cancer lineages are Regulation of nervous system process, Serotonin metabolic process, and Regulation of myoblast fusion. Each is linked with RNF180 in more than 8 cancer types. Because this analysis shows association rather than direction, both RNF180-to-partner and partner-to-RNF180 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nervous system process grouped by RNF180-low versus RNF180-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF180→partner) and Y-score (partner→RNF180) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of nervous system process →	-0.043	-0.535	.003	.002	3	9
PANCREAS	Serotonin metabolic process →	-0.193	-0.583	<.001	<.001	3	9
STOMACH	Regulation of myoblast fusion →	+0.104	+0.290	.001	.005	3	8
STOMACH	Negative regulation of myoblast fusion →	+0.117	+0.275	<.001	.001	3	8
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.114	+0.275	<.001	.001	3	8
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.100	+0.230	.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,130 associations by consensus.

Regulation of nervous system process by RNF180 expression — OVARY

Explore this box plot interactively →