RNF175

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RNF175 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RNF175-associated genes across cancer lineages are ASB17 and GJD2. Each is linked with RNF175 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF175-to-partner and partner-to-RNF175 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB17 grouped by RNF175-low versus RNF175-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF175→partner) and Y-score (partner→RNF175) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaASB17 →+0.012+5.209<.001.00531
LARGE_INTESTINEGJD2 →+0.004+4.437<.001.00431
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ASB17 by RNF175 expression — BLOOD_Lymphoma

Box plot of ASB17 in RNF175-low vs RNF175-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration