RNF170

Across TCGA patient cohorts, RNF170 protein abundance is significantly associated with the RNA expression of many other genes, with 8,615 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RNF170-associated genes across cancer lineages are TIMELESS, PTTG1, and SLC20A2. Each is linked with RNF170 in more than 3 cancer types. Because this analysis shows association rather than direction, both RNF170-to-partner and partner-to-RNF170 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF170 versus TIMELESS in UCEC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF170→partner) and Y-score (partner→RNF170) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIMELESS →	-0.824	-0.493	.001	<.001	3	4
UCEC	PTTG1 →	-1.032	-0.466	.002	.001	3	4
GBM	SLC20A2 →	+0.595	+0.278	.001	.005	3	4
GBM	HMGXB4 →	-0.360	-0.255	<.001	.002	3	3
UCEC	PRMT5 →	-0.778	-0.553	.003	<.001	3	3
COAD	GABPB1 →	-0.327	-0.311	.004	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,615 associations by consensus.

RNF170 vs TIMELESS — UCEC

Explore this scatter interactively →