RNF170

Across TCGA cell cohorts, RNF170 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,526 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNF170-associated GO terms across cancer lineages are Interkinetic nuclear migration, Vacuole organization, and ERAD pathway. Each is linked with RNF170 in more than 14 cancer types. Because this analysis shows association rather than direction, both RNF170-to-partner and partner-to-RNF170 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Interkinetic nuclear migration grouped by RNF170-low versus RNF170-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF170→partner) and Y-score (partner→RNF170) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Interkinetic nuclear migration →	+0.097	+0.828	<.001	.001	3	15
BLOOD_Myeloma	Vacuole organization →	+0.049	+1.456	.002	.002	3	11
LARGE_INTESTINE	ERAD pathway →	+0.073	+0.794	<.001	<.001	3	11
LARGE_INTESTINE	Vacuolar transport →	+0.049	+0.627	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Lysosome organization →	+0.048	+0.728	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Lytic vacuole organization →	+0.048	+0.728	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,526 associations by consensus.

Interkinetic nuclear migration by RNF170 expression — LUNG_SCLC

Explore this box plot interactively →