RNF166

Across TCGA patient cohorts, RNF166 RNA expression is significantly associated with the mutation status of many other genes, with 12,512 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF166-associated genes across cancer lineages are TP53, NF1, and TTN. Each is linked with RNF166 in more than 3 cancer types. Because this analysis shows association rather than direction, both RNF166-to-partner and partner-to-RNF166 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by RNF166-low versus RNF166-high in LIHC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF166→partner) and Y-score (partner→RNF166) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	TP53 →	+1.007	+0.307	<.001	<.001	3	4
UCEC	NF1 →	+1.766	+0.491	<.001	<.001	3	4
LGG	TTN →	+1.536	+0.204	.001	.002	3	3
UCEC	CENPF →	+1.436	+0.451	<.001	<.001	3	3
UCEC	FLG →	+1.486	+0.383	<.001	<.001	3	3
UCEC	FAT3 →	+1.343	+0.364	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,512 associations by consensus.

TP53 by RNF166 expression — LIHC

Explore this box plot interactively →