RNF165

Across TCGA patient cohorts, RNF165 mutation is significantly associated with the RNA expression of many other genes, with 3,841 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF165-associated genes across cancer lineages are LSM3, PMS2P4, and TIPIN. Each is linked with RNF165 in more than 2 cancer types. Because this analysis shows association rather than direction, both RNF165-to-partner and partner-to-RNF165 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LSM3 grouped by RNF165-low versus RNF165-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF165→partner) and Y-score (partner→RNF165) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LSM3 →	+0.539	+2.050	<.001	<.001	3	3
UCEC	PMS2P4 →	+0.313	+2.094	.004	<.001	3	3
UCEC	TIPIN →	+0.451	+1.828	<.001	<.001	3	3
UCEC	E2F2 →	+0.475	+2.491	.003	<.001	3	3
UCEC	SF3B2 →	+0.390	+3.108	<.001	<.001	3	3
UCEC	EMC4 →	+0.310	+1.805	.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,841 associations by consensus.

LSM3 by RNF165 expression — UCEC

Explore this box plot interactively →