RNF165

Across TCGA patient cohorts, RNF165 mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF165-associated genes across cancer lineages are Bid, Shc_pY317, and TFRC. Each is linked with RNF165 in more than 2 cancer types. Because this analysis shows association rather than direction, both RNF165-to-partner and partner-to-RNF165 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bid grouped by RNF165-low versus RNF165-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF165→partner) and Y-score (partner→RNF165) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Bid →	+0.178	+2.841	<.001	.033	3	3
UCEC	Shc_pY317 →	-0.181	-1.353	<.001	.015	3	2
UCEC	TFRC →	+0.520	+3.807	.001	<.001	3	2
UCEC	ATM →	-0.447	-2.649	.001	<.001	3	2
UCEC	CDK1 →	+0.121	+1.713	.011	.024	3	2
UCEC	c-Met_pY1235 →	+0.050	+1.372	.030	.022	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Bid by RNF165 expression — COAD

Explore this box plot interactively →