RNF165

Across TCGA cell cohorts, RNF165 mutation is significantly associated with the RNA expression of many other genes, with 173 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RNF165-associated genes across cancer lineages are P2RY10, GRPEL1, and RIC8B. Each is linked with RNF165 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF165-to-partner and partner-to-RNF165 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, P2RY10 grouped by RNF165-low versus RNF165-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF165→partner) and Y-score (partner→RNF165) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	P2RY10 →	+0.100	+4.263	<.001	.002	3	1
LARGE_INTESTINE	GRPEL1 →	+0.599	+3.299	<.001	.004	3	1
LARGE_INTESTINE	RIC8B →	+0.571	+3.212	.002	.006	3	1
LARGE_INTESTINE	ATP5PB →	+0.528	+3.212	.001	.006	3	1
LARGE_INTESTINE	COQ3 →	+0.695	+3.212	.005	.006	3	1
LARGE_INTESTINE	PEMT →	+0.607	+3.299	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 173 associations by consensus.

P2RY10 by RNF165 expression — SKIN

Explore this box plot interactively →