RNF157

Across TCGA pan-cancer cohorts, RNF157 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RNF157 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNF157 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNF157 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

KICH, BRCA, and UCEC are the cancer types where RNF157 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	All	0.102	0.848	.004	13	view →
BRCA	OS	Median	All	0.206	0.580	.014	4	view →
UCEC	DFS	Median	All	1.000	0.631	.034	4	view →
LIHC	DFS	Median	All	0.141	0.555	.017	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RNF157–KICH (DFS)

Open the KICH breakdown →