RNF152

Across TCGA pan-cancer cohorts, RNF152 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated RNF152 data layer compared with 29 for mass-spec protein.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher RNF152 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RNF152 expression acts as an unfavorable survival marker.

PAAD, LUSC, and UCEC are the cancer types where RNF152 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Median	All	0.140	0.590	<.001	24	view →
LUSC	OS	Median	II,III,IV	0.080	0.743	<.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

RNF152–PAAD (OS)

Open the PAAD breakdown →