RNF151

Across TCGA patient cohorts, RNF151 mutation is significantly associated with the RNA expression of many other genes, with 850 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF151-associated genes across cancer lineages are RPL31P47, SSRP1, and MTA2. Each is linked with RNF151 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF151-to-partner and partner-to-RNF151 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL31P47 grouped by RNF151-low versus RNF151-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF151→partner) and Y-score (partner→RNF151) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL31P47 →	+0.400	+3.121	<.001	.001	3	2
UCEC	SSRP1 →	+0.687	+3.343	.005	.005	3	1
UCEC	MTA2 →	+0.570	+3.386	.001	.004	3	1
UCEC	CCDC15 →	+0.640	+3.354	<.001	.005	3	1
UCEC	ANKRD50 →	+0.890	+3.354	<.001	.005	3	1
UCEC	MIA3 →	+0.883	+3.343	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 850 associations by consensus.

RPL31P47 by RNF151 expression — UCEC

Explore this box plot interactively →