RNF150

Across TCGA patient cohorts, RNF150 mutation is significantly associated with the RNA expression of many other genes, with 2,312 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF150-associated genes across cancer lineages are CCNB2, SCNN1B, and ING2. Each is linked with RNF150 in more than 2 cancer types. Because this analysis shows association rather than direction, both RNF150-to-partner and partner-to-RNF150 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCNB2 grouped by RNF150-low versus RNF150-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF150→partner) and Y-score (partner→RNF150) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCNB2 →	+0.634	+3.732	.002	<.001	3	3
UCEC	SCNN1B →	-1.542	-2.392	<.001	<.001	3	3
UCEC	ING2 →	+0.496	+2.435	<.001	<.001	3	3
UCEC	MSANTD3 →	+0.514	+3.016	<.001	<.001	3	3
UCEC	BIRC5 →	+0.885	+2.906	<.001	<.001	3	3
HNSC	CCNHP1 →	+0.064	+5.015	.005	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,312 associations by consensus.

CCNB2 by RNF150 expression — UCEC

Explore this box plot interactively →