RNF149

Across TCGA patient cohorts, RNF149 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,048 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RNF149-associated proteins across cancer lineages are ACTR2, MNDA, and CDA. Each is linked with RNF149 in more than 5 cancer types. Because this analysis shows association rather than direction, both RNF149-to-partner and partner-to-RNF149 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF149 versus ACTR2 in GBM, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF149→partner) and Y-score (partner→RNF149) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ACTR2 →	+0.197	+0.826	<.001	<.001	3	6
GBM	MNDA →	+0.970	+0.755	<.001	<.001	3	6
GBM	CDA →	+0.676	+0.738	.002	<.001	3	5
GBM	HK3 →	+0.986	+0.699	<.001	<.001	3	5
GBM	TGFB1 →	+0.488	+0.876	<.001	<.001	3	5
GBM	NCF2 →	+0.756	+0.636	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,048 associations by consensus.

RNF149 vs ACTR2 — GBM

Explore this scatter interactively →