RNF149

Across TCGA patient cohorts, RNF149 protein abundance is significantly associated with the RNA expression of many other genes, with 7,843 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RNF149-associated genes across cancer lineages are ZNF214, BBS9, and NEK3. Each is linked with RNF149 in more than 3 cancer types. Because this analysis shows association rather than direction, both RNF149-to-partner and partner-to-RNF149 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF149 versus ZNF214 in BRCA, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF149→partner) and Y-score (partner→RNF149) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF214 →	-0.604	-0.361	<.001	<.001	3	4
HNSC	BBS9 →	-0.641	-0.482	.001	<.001	3	4
HNSC	NEK3 →	-0.762	-0.408	<.001	.001	3	4
HNSC	ZMAT1 →	-1.062	-0.529	<.001	<.001	3	4
LSCC	PURG →	-0.480	-0.223	<.001	<.001	3	4
BRCA	MAGED2 →	-0.899	-0.287	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,843 associations by consensus.

RNF149 vs ZNF214 — BRCA

Explore this scatter interactively →