RNF148

Across TCGA cell cohorts, RNF148 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,410 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RNF148-associated GO terms across cancer lineages are Regulation of myoblast fusion, Microglia differentiation, and Positive regulation of integrin activation. Each is linked with RNF148 in more than 5 cancer types. Because this analysis shows association rather than direction, both RNF148-to-partner and partner-to-RNF148 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by RNF148-low versus RNF148-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF148→partner) and Y-score (partner→RNF148) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.086	+0.236	<.001	.008	3	6
LUNG_NSCLC_LUSC	Microglia differentiation →	-0.179	-0.200	.001	.007	3	6
BONE	Positive regulation of integrin activation →	-0.273	-1.070	<.001	.001	3	6
BLOOD_Lymphoma	Regulation of syncytium formation by plasma membrane fusion →	+0.084	+0.245	<.001	.007	3	6
BONE	Ameboidal-type cell migration →	-0.087	-0.892	<.001	.007	3	6
LUNG_NSCLC_LUAD	Lipoprotein catabolic process →	+0.095	+0.223	.002	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,410 associations by consensus.

Regulation of myoblast fusion by RNF148 expression — BLOOD_Lymphoma

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