RNF14

Across TCGA patient cohorts, RNF14 mutation is significantly associated with the RNA expression of many other genes, with 595 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF14-associated genes across cancer lineages are RN7SL504P, RNU6-1245P, and MIR4478. Each is linked with RNF14 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF14-to-partner and partner-to-RNF14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL504P grouped by RNF14-low versus RNF14-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF14→partner) and Y-score (partner→RNF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL504P →	+0.100	+5.900	<.001	<.001	3	2
CESC	RNU6-1245P →	+0.389	+5.060	<.001	.001	3	2
KIRC	MIR4478 →	+0.402	+5.038	<.001	.009	3	2
COAD	NICN2P →	+0.140	+3.870	.002	.006	3	2
HNSC	RPL13P →	+0.059	+4.578	<.001	.008	3	1
BLCA	RNU6-225P →	+0.352	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 595 associations by consensus.

RN7SL504P by RNF14 expression — SKCM

Explore this box plot interactively →