RNF14

Across TCGA cell cohorts, RNF14 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible RNF14-associated genes across cancer lineages are ASB17, IL3, and OR10K1. Each is linked with RNF14 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF14-to-partner and partner-to-RNF14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB17 grouped by RNF14-low versus RNF14-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF14→partner) and Y-score (partner→RNF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	ASB17 →	+0.022	+5.029	<.001	.006	3	1
LUNG_SCLC	IL3 →	+0.055	+5.029	<.001	.006	3	1
LUNG_SCLC	OR10K1 →	+0.569	+5.029	<.001	.006	3	1
LUNG_SCLC	OR10K2 →	+0.026	+5.643	<.001	.002	3	1
LUNG_SCLC	PRAMEF10 →	+1.180	+5.643	<.001	.002	3	1
LUNG_SCLC	PRAMEF17 →	+0.013	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

ASB17 by RNF14 expression — LUNG_SCLC

Explore this box plot interactively →