RNF135

Across TCGA cell cohorts, RNF135 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,130 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RNF135-associated GO terms across cancer lineages are Free ubiquitin chain polymerization, Ubiquitin recycling, and Xenophagy. Each is linked with RNF135 in more than 8 cancer types. Because this analysis shows association rather than direction, both RNF135-to-partner and partner-to-RNF135 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Free ubiquitin chain polymerization grouped by RNF135-low versus RNF135-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF135→partner) and Y-score (partner→RNF135) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Free ubiquitin chain polymerization →	-0.192	-2.119	<.001	<.001	3	9
BLOOD_Myeloma	Ubiquitin recycling →	+0.076	+0.881	.005	.007	3	8
SOFT_TISSUE	Xenophagy →	+0.147	+1.525	.003	.001	3	8
OESOPHAGUS	Protein polyubiquitination →	+0.051	+0.948	<.001	<.001	3	8
SOFT_TISSUE	Protein complex oligomerization →	+0.048	+1.916	<.001	<.001	3	7
OESOPHAGUS	Cellular response to epidermal growth factor stimulus →	+0.079	+0.672	.002	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,130 associations by consensus.

Free ubiquitin chain polymerization by RNF135 expression — BONE

Explore this box plot interactively →