Across TCGA cell cohorts, RNF133 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNF133-associated genes across cancer lineages are R3HDML, NANOG, and CCDC182. Each is linked with RNF133 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF133-to-partner and partner-to-RNF133 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF133→partner) and Y-score (partner→RNF133) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	R3HDML →	+0.013	+4.569	<.001	.003	3	2
SKIN	NANOG →	+0.050	+4.095	<.001	.009	3	1
SKIN	CCDC182 →	+0.041	+5.217	<.001	<.001	3	1
SKIN	OR5B3 →	+0.044	+4.415	<.001	.007	3	1
LUNG_NSCLC_LUAD	OR6C70 →	+0.365	+5.266	<.001	.001	3	1
BLOOD_Leukemia	PRM2 →	+0.027	+3.969	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

RNF133 survival (RNA) · tumor vs normal (RNA) · all RNF133 data types