RNF130

Across TCGA patient cohorts, RNF130 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,842 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RNF130-associated proteins across cancer lineages are RPS5, TBC1D9B, and RUFY1. Each is linked with RNF130 in more than 4 cancer types. Because this analysis shows association rather than direction, both RNF130-to-partner and partner-to-RNF130 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF130 versus RPS5 in GBM, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF130→partner) and Y-score (partner→RNF130) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPS5 →	-0.200	-0.410	<.001	<.001	3	5
OV	TBC1D9B →	+0.281	+0.525	<.001	<.001	3	5
OV	RUFY1 →	+0.315	+0.482	.003	<.001	3	4
HNSC	AKR1B1 →	+0.529	+0.489	<.001	<.001	2	5
BRCA	AFG3L2 →	-0.483	-0.465	<.001	<.001	3	4
PDAC	APOE →	+0.621	+0.406	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,842 associations by consensus.

RNF130 vs RPS5 — GBM

Explore this scatter interactively →