RNF130

Across TCGA cell cohorts, RNF130 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,983 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNF130-associated GO terms across cancer lineages are Cardiac septum cell differentiation, Atrioventricular node cell differentiation, and Atrioventricular node cell development. Each is linked with RNF130 in more than 10 cancer types. Because this analysis shows association rather than direction, both RNF130-to-partner and partner-to-RNF130 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cardiac septum cell differentiation grouped by RNF130-low versus RNF130-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF130→partner) and Y-score (partner→RNF130) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Cardiac septum cell differentiation →	+0.150	+1.375	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Atrioventricular node cell differentiation →	+0.150	+1.375	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Atrioventricular node cell development →	+0.150	+1.375	<.001	<.001	3	11
STOMACH	Regulation of blood circulation →	-0.065	-1.961	.003	.006	3	7
LUNG_SCLC	Positive regulation of translational initiation →	+0.080	+1.562	.006	.005	2	8
UPPER_AERODIGESTIVE_TRACT	Regulation of heart rate by cardiac conduction →	-0.220	-1.722	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,983 associations by consensus.

Cardiac septum cell differentiation by RNF130 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →