RNF13

Across TCGA pan-cancer cohorts, RNF13 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated RNF13 data layer compared with 22 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNF13 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RNF13 expression acts as an unfavorable survival marker.

UCEC and SKCM are the cancer types where RNF13 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	IV	0.133	0.754	<.001	12	view →
SKCM	OS	Median	III,IV	0.232	0.705	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

RNF13–UCEC (OS)

Open the UCEC breakdown →