RNF13

Across TCGA pan-cancer cohorts, RNF13 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RNF13 data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNF13 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNF13 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

UCEC, CCRCC, and HNSC are the cancer types where RNF13 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	II,III,IV	0.204	0.692	.012	20	view →
CCRCC	DFS	Tertile	All	0.867	0.395	.014	11	view →
HNSC	OS	Quartile	II,III,IV	0.921	1.000	.026	7	view →
PDAC	DFS	Quartile	II,III,IV	0.628	0.822	.038	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RNF13–UCEC (DFS)

Open the UCEC breakdown →