RNF13

Across TCGA cell cohorts, RNF13 mutation is significantly associated with the mutation status of many other genes, with 1,086 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RNF13-associated genes across cancer lineages are MAP2K7, DGKD, and DPEP1. Each is linked with RNF13 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF13-to-partner and partner-to-RNF13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAP2K7 grouped by RNF13-low versus RNF13-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF13→partner) and Y-score (partner→RNF13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	MAP2K7 →	+4.824	+5.392	.004	.004	1	2
SKIN	DGKD →	+4.239	+5.053	.007	.007	1	2
SKIN	DPEP1 →	+4.824	+5.392	.004	.004	1	2
SKIN	TIMP3 →	+5.824	+5.824	.002	.002	1	2
SKIN	PACSIN2 →	+4.239	+5.053	.007	.007	1	2
SKIN	TRIP11 →	+4.239	+5.053	.007	.007	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,086 associations by consensus.

MAP2K7 by RNF13 expression — SKIN

Explore this box plot interactively →