RNF126P1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNF126P1 mutation is significantly associated with the RNA expression of many other genes, with 722 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF126P1-associated genes across cancer lineages are RN7SL385P, RNA5SP436, and OR9Q2. Each is linked with RNF126P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF126P1-to-partner and partner-to-RNF126P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL385P grouped by RNF126P1-low versus RNF126P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF126P1→partner) and Y-score (partner→RNF126P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL385P →+0.291+2.358.001.00832
UCECRNA5SP436 →+0.248+3.522.004.00332
COADOR9Q2 →+0.041+4.136<.001.00832
CESCMICG →+0.205+4.969.006.00431
CESCRCC2P5 →+0.029+5.837<.001.00131
CESCLINC02061 →+0.088+4.812<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 722 associations by consensus.

RN7SL385P by RNF126P1 expression — UCEC

Box plot of RN7SL385P in RNF126P1-low vs RNF126P1-high samples in UCEC.

Explore this box plot interactively →

Exploration