RNF126P1

Across TCGA patient cohorts, RNF126P1 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF126P1-associated genes across cancer lineages are ERK2, Rictor_pT1135, and Caspase-7-cleavedD198. Each is linked with RNF126P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF126P1-to-partner and partner-to-RNF126P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by RNF126P1-low versus RNF126P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF126P1→partner) and Y-score (partner→RNF126P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.260	+3.000	.019	.037	3	1
UCEC	Rictor_pT1135 →	-0.123	-3.000	.038	.037	3	1
UCEC	Caspase-7-cleavedD198 →	+0.824	+2.827	.016	.035	3	1
UCEC	CD20 →	+0.174	+2.827	.022	.035	3	1
UCEC	GSK3-a-b →	+0.194	+3.000	.012	.037	2	1
UCEC	p38-MAPK_pT180_Y182 →	-0.995	-2.986	<.001	.037	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

ERK2 by RNF126P1 expression — UCEC

Explore this box plot interactively →