RNF123

Across TCGA patient cohorts, RNF123 protein abundance is significantly associated with the RNA expression of many other genes, with 4,376 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF123-associated genes across cancer lineages are HBA2, HBA1, and HBB. Each is linked with RNF123 in more than 6 cancer types. Because this analysis shows association rather than direction, both RNF123-to-partner and partner-to-RNF123 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF123 versus HBA2 in GBM, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF123→partner) and Y-score (partner→RNF123) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HBA2 →	+1.664	+0.340	<.001	<.001	3	7
GBM	HBA1 →	+1.547	+0.321	<.001	<.001	3	7
BRCA	HBB →	+2.023	+0.415	<.001	<.001	3	6
CCRCC	PF4 →	+0.848	+0.452	<.001	<.001	3	5
GBM	ALAS2 →	+0.665	+0.217	<.001	<.001	3	5
CCRCC	HEMGN →	+0.579	+0.396	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,376 associations by consensus.

RNF123 vs HBA2 — GBM

Explore this scatter interactively →