RNF123

Across TCGA cell cohorts, RNF123 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,869 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible RNF123-associated GO terms across cancer lineages are Regulation of autophagosome maturation, Viral translational termination-reinitiation, and Nucleic acid catabolic process. Each is linked with RNF123 in more than 13 cancer types. Because this analysis shows association rather than direction, both RNF123-to-partner and partner-to-RNF123 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of autophagosome maturation grouped by RNF123-low versus RNF123-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF123→partner) and Y-score (partner→RNF123) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of autophagosome maturation →	+0.093	+0.727	<.001	<.001	3	14
LARGE_INTESTINE	Viral translational termination-reinitiation →	+0.104	+0.552	<.001	<.001	3	14
CNS	Nucleic acid catabolic process →	+0.049	+0.512	<.001	<.001	3	13
OESOPHAGUS	Cytosolic transport →	+0.056	+0.608	.003	.001	3	13
LARGE_INTESTINE	Microtubule polymerization →	+0.113	+0.478	<.001	.002	3	13
BLOOD_Lymphoma	Nucleic acid transport →	+0.089	+0.758	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,869 associations by consensus.

Regulation of autophagosome maturation by RNF123 expression — OVARY

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