RNF121

Across TCGA cell cohorts, RNF121 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,961 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RNF121-associated GO terms across cancer lineages are Vacuole organization, Protein-containing complex disassembly, and Endoplasmic reticulum to cytosol transport. Each is linked with RNF121 in more than 13 cancer types. Because this analysis shows association rather than direction, both RNF121-to-partner and partner-to-RNF121 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuole organization grouped by RNF121-low versus RNF121-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF121→partner) and Y-score (partner→RNF121) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Vacuole organization →	+0.073	+0.746	<.001	<.001	3	14
URINARY_TRACT	Protein-containing complex disassembly →	+0.066	+0.780	.001	.003	3	13
STOMACH	Endoplasmic reticulum to cytosol transport →	+0.129	+0.649	.002	.002	3	12
STOMACH	Retrograde protein transport, ER to cytosol →	+0.129	+0.649	.002	.002	3	12
STOMACH	Macroautophagy →	+0.069	+0.722	.002	<.001	3	12
STOMACH	Establishment of protein localization to membrane →	+0.060	+0.472	<.001	.008	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,961 associations by consensus.

Vacuole organization by RNF121 expression — STOMACH

Explore this box plot interactively →