RNF114

Across TCGA pan-cancer cohorts, RNF114 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated RNF114 data layer compared with 20 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RNF114 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNF114 expression acts as an unfavorable survival marker.

KIRP and UCEC are the cancer types where RNF114 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	All	0.133	0.605	.014	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

RNF114–KIRP (DFS)

Open the KIRP breakdown →