RNF114

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNF114 protein abundance is significantly associated with the RNA expression of many other genes, with 9,494 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RNF114-associated genes across cancer lineages are CSE1L, DDX27, and MYBL2. Each is linked with RNF114 in more than 6 cancer types. Because this analysis shows association rather than direction, both RNF114-to-partner and partner-to-RNF114 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF114 versus CSE1L in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF114→partner) and Y-score (partner→RNF114) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCSE1L →+0.668+0.331<.001<.00137
COADDDX27 →+0.862+0.365<.001<.00136
BRCAMYBL2 →+1.225+0.284<.001<.00135
COADDPM1 →+0.610+0.347<.001<.00135
UCECAURKA →+0.913+0.252<.001<.00135
COADRAE1 →+0.663+0.280<.001.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,494 associations by consensus.

RNF114 vs CSE1L — UCEC

Per-sample scatter of RNF114 vs CSE1L in UCEC (Pearson r = 0.39).

Explore this scatter interactively →

Exploration