RNF113A

Across TCGA patient cohorts, RNF113A mutation is significantly associated with the RNA expression of many other genes, with 1,433 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF113A-associated genes across cancer lineages are THAP12P5, SPRR4, and MIR921. Each is linked with RNF113A in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF113A-to-partner and partner-to-RNF113A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, THAP12P5 grouped by RNF113A-low versus RNF113A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF113A→partner) and Y-score (partner→RNF113A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	THAP12P5 →	+0.026	+3.669	<.001	.006	3	2
BRCA	SPRR4 →	+0.569	+4.211	<.001	.003	3	2
COAD	MIR921 →	+1.146	+4.666	<.001	.005	3	2
COAD	MIR1205 →	+1.821	+4.042	<.001	.005	3	2
COAD	MTCYBP32 →	+0.756	+4.428	<.001	.002	3	2
COAD	MIR6509 →	+0.917	+3.951	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,433 associations by consensus.

THAP12P5 by RNF113A expression — SKCM

Explore this box plot interactively →