RNF111

Across TCGA patient cohorts, RNF111 protein abundance is significantly associated with the RNA expression of many other genes, with 556 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RNF111-associated genes across cancer lineages are TGM5, PTPMT1, and DAO. Each is linked with RNF111 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF111-to-partner and partner-to-RNF111 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF111 versus TGM5 in LSCC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF111→partner) and Y-score (partner→RNF111) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TGM5 →	+1.111	+0.447	<.001	<.001	3	1
LSCC	PTPMT1 →	-0.396	-0.338	.006	.007	3	1
LSCC	DAO →	-0.058	-0.377	.009	.004	3	1
LSCC	ARRDC4 →	+0.700	+0.339	.004	.003	3	1
LSCC	HORMAD1 →	+1.958	+0.313	<.001	.001	3	1
LSCC	SNTG1 →	-0.021	-0.375	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 556 associations by consensus.

RNF111 vs TGM5 — LSCC

Explore this scatter interactively →