RNF111

Across TCGA cell cohorts, RNF111 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,293 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNF111-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription initiation, Nuclear export, and Negative regulation of transcription initiation by RNA polymerase II. Each is linked with RNF111 in more than 15 cancer types. Because this analysis shows association rather than direction, both RNF111-to-partner and partner-to-RNF111 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA-templated transcription initiation grouped by RNF111-low versus RNF111-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF111→partner) and Y-score (partner→RNF111) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of DNA-templated transcription initiation →	+0.122	+0.679	.003	.003	3	16
LARGE_INTESTINE	Nuclear export →	+0.091	+0.752	<.001	<.001	3	16
STOMACH	Negative regulation of transcription initiation by RNA polymerase II →	+0.122	+0.679	.003	.003	3	16
LARGE_INTESTINE	Viral translational termination-reinitiation →	+0.086	+0.647	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.076	+1.096	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.078	+0.757	<.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,293 associations by consensus.

Negative regulation of DNA-templated transcription initiation by RNF111 expression — STOMACH

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