RND3

Across TCGA cell cohorts, RND3 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RND3-associated genes across cancer lineages are CBY1, FAM124A, and TNK1. Each is linked with RND3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RND3-to-partner and partner-to-RND3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBY1 grouped by RND3-low versus RND3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RND3→partner) and Y-score (partner→RND3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CBY1 →	+0.746	+3.160	<.001	.006	3	1
LARGE_INTESTINE	FAM124A →	+0.748	+3.295	<.001	.006	3	1
LARGE_INTESTINE	TNK1 →	+0.848	+3.064	.003	.009	3	1
LARGE_INTESTINE	C4orf47 →	+0.451	+3.371	<.001	.004	3	1
LARGE_INTESTINE	FBXO42 →	+0.641	+3.064	.001	.009	3	1
LARGE_INTESTINE	SLC25A24 →	+0.697	+3.067	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

CBY1 by RND3 expression — LARGE_INTESTINE

Explore this box plot interactively →