RND2

Across TCGA patient cohorts, RND2 mutation is significantly associated with the RNA expression of many other genes, with 420 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RND2-associated genes across cancer lineages are LCEP1, GRIK4, and MAT1A. Each is linked with RND2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RND2-to-partner and partner-to-RND2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCEP1 grouped by RND2-low versus RND2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RND2→partner) and Y-score (partner→RND2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LCEP1 →	+0.079	+7.930	<.001	.008	3	2
UCEC	GRIK4 →	-0.513	-3.700	.009	.001	3	1
UCEC	MAT1A →	-1.053	-3.576	.002	.002	3	1
UCEC	VPS37A →	+0.575	+2.595	.006	.006	3	1
UCEC	NTAN1 →	+0.611	+2.638	<.001	.005	3	1
UCEC	MX1 →	-1.768	-3.451	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 420 associations by consensus.

LCEP1 by RND2 expression — LUAD

Explore this box plot interactively →