RND2

Across TCGA patient cohorts, RND2 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RND2-associated genes across cancer lineages are eEF2, ETS-1, and Lck. Each is linked with RND2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RND2-to-partner and partner-to-RND2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by RND2-low versus RND2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RND2→partner) and Y-score (partner→RND2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.494	+3.459	.005	.005	3	2
UCEC	ETS-1 →	+0.331	+3.000	.038	.036	3	1
UCEC	Lck →	+0.264	+2.321	.008	.035	3	1
UCEC	Notch1 →	+0.193	+3.013	.006	.018	3	1
UCEC	PRDX1 →	+0.264	+3.000	.010	.036	3	1
UCEC	Annexin-1 →	+0.675	+2.827	.010	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

eEF2 by RND2 expression — UCEC

Explore this box plot interactively →