Across TCGA patient cohorts, RNASEK RNA expression is significantly associated with the mutation status of many other genes, with 10,511 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNASEK-associated genes across cancer lineages are TP53, DNAH2, and USP31. Each is linked with RNASEK in more than 4 cancer types. Because this analysis shows association rather than direction, both RNASEK-to-partner and partner-to-RNASEK results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASEK→partner) and Y-score (partner→RNASEK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	TP53 →	-1.450	-0.199	<.001	<.001	3	5
COAD	DNAH2 →	+1.888	+0.235	.003	.005	3	4
UCEC	USP31 →	+2.042	+0.317	<.001	<.001	3	4
UCEC	PIKFYVE →	+1.990	+0.281	<.001	<.001	3	4
UCEC	PPL →	+2.743	+0.346	<.001	<.001	3	4
UCEC	PTPRB →	+1.990	+0.318	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,511 associations by consensus.

Exploration

RNASEK survival (RNA) · tumor vs normal (RNA) · all RNASEK data types