RNASEK-C17orf49

Across TCGA pan-cancer cohorts, RNASEK-C17orf49 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNASEK-C17orf49 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNASEK-C17orf49 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNASEK-C17orf49 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PAAD show a favorable association.

KIRC, UCEC, and LUAD are the cancer types where RNASEK-C17orf49 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.835	0.906	<.001	94	view →
UCEC	DFS	Median	All	0.743	0.512	<.001	80	view →
LUAD	DFS	Median	II,III,IV	0.557	0.737	.004	23	view →
PRAD	DFS	Median	All	0.708	0.875	<.001	22	view →
READ	OS	Median	All	0.501	0.824	.007	14	view →
UCS	OS	Tertile	II,III,IV	0.260	0.610	.014	14	view →
COAD	DFS	Median	II,III,IV	0.382	0.664	.005	13	view →
LGG	DFS	Tertile	All	0.753	0.872	.014	11	view →
ACC	DFS	Median	All	0.240	0.712	.012	11	view →
THCA	DFS	Quartile	III,IV	0.726	0.891	.020	10	view →
PAAD	OS	Quartile	All	0.585	0.294	.007	7	view →
BRCA	OS	Median	IV	0.568	0.187	.021	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RNASEK-C17orf49–KIRC (DFS)

Open the KIRC breakdown →