RNASEH2C

Across TCGA patient cohorts, RNASEH2C protein abundance is significantly associated with the RNA expression of many other genes, with 11,178 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RNASEH2C-associated genes across cancer lineages are RNASEH2B, MIR17HG, and RBL1. Each is linked with RNASEH2C in more than 8 cancer types. Because this analysis shows association rather than direction, both RNASEH2C-to-partner and partner-to-RNASEH2C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNASEH2C versus RNASEH2B in HNSC, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASEH2C→partner) and Y-score (partner→RNASEH2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNASEH2B →	+0.610	+0.311	<.001	<.001	3	9
HNSC	MIR17HG →	+0.908	+0.406	<.001	<.001	3	7
HNSC	RBL1 →	+0.739	+0.338	<.001	<.001	3	6
OV	CKAP2 →	+0.736	+0.311	<.001	<.001	3	6
HNSC	MRPS31 →	+0.456	+0.253	.001	.001	3	5
UCEC	EXOSC8 →	+0.496	+0.339	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,178 associations by consensus.

RNASEH2C vs RNASEH2B — HNSC

Explore this scatter interactively →