RNASEH2C

Across TCGA patient cohorts, RNASEH2C protein abundance is significantly associated with the protein abundance of many other proteins, with 16,993 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RNASEH2C-associated proteins across cancer lineages are RNASEH2A, RNASEH2B, and TRPM4. Each is linked with RNASEH2C in more than 8 cancer types. Because this analysis shows association rather than direction, both RNASEH2C-to-partner and partner-to-RNASEH2C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNASEH2C versus RNASEH2A in UCEC, with a Pearson correlation of 0.80.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASEH2C→partner) and Y-score (partner→RNASEH2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNASEH2A →	+0.417	+0.484	<.001	<.001	3	9
LSCC	RNASEH2B →	+0.533	+0.446	<.001	<.001	3	9
UCEC	TRPM4 →	-0.518	-0.264	<.001	<.001	3	7
GBM	GABPA →	+0.319	+0.528	.001	<.001	3	7
GBM	GTF2F2 →	+0.380	+0.310	<.001	<.001	3	7
UCEC	SLC44A1 →	-0.489	-0.271	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,993 associations by consensus.

RNASEH2C vs RNASEH2A — UCEC

Explore this scatter interactively →