RNASEH2C

Across TCGA patient cohorts, RNASEH2C mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNASEH2C-associated genes across cancer lineages are Memory B-cells and CD8+ naive T-cells. Each is linked with RNASEH2C in more than 1 cancer types. Because this analysis shows association rather than direction, both RNASEH2C-to-partner and partner-to-RNASEH2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Memory B-cells grouped by RNASEH2C-low versus RNASEH2C-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASEH2C→partner) and Y-score (partner→RNASEH2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Memory B-cells →	+0.039	+2.374	.013	.039	3	1
UCEC	CD8+ naive T-cells →	+0.046	+3.042	.002	.018	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Memory B-cells by RNASEH2C expression — UCEC

Explore this box plot interactively →